‹ Return to Courses

Rett Syndrome: Biology, Development, and Prognosis

Course #: 03-698

Price: $36.00

Take the Exam 

CE Credit Hours: 4.00 Continuing Education Credit Hours

Take the Exam 

How to Take This Course:

  • 1 View Course Worksheet -  View the course worksheet or print it out to review later
  • 2 Read the Course Material -  As you read through, mark your answers on the course worksheet to be prepared for the exam
  • 3 Take Exam -  You must achieve a score of 70% or higher in order to earn credit for the course.
  • You don't need to pay for an exam until AFTER you pass it. If you have any questions or need more information, please click here.

CEU Course Description 


Rett syndrome (RTT) is a rare disease but still one of the most abundant causes for intellectual disability in females. The first goal of this CEU course is to explore the biological pathways of RTT and the journey from the MECP2 gene through the transcription process, known changes in metabolite levels, and the different phenotype expressions. We will also explore a natural history study to examine the differences in early developmental skills in classic RTT vs. atypical RTT and the clinical severity. This section will look further into gross and fine motor skills as well as repetitive and expressive communication. Finally, the course will delve into a twenty-year surveillance of RTT including survival and how both physical and function characteristics persist into adulthood. Here we look at a retrospective study of birth and death information for 396 females with RTT and investigate instance of epilepsy, musculoskeletal abnormalities, gastrointestinal dysfunction, and adult behavior. The reading materials for this course include articles from the Orphanet Journal of Rare Diseases and the Journal of Neurodevelopmental Disorders,

CEU Course Objectives

  1. Enumerate the most abundant causes of death of RTT females.
  2. Explain the main function of MECP2.
  3. Investigate in which tissue the MECP2 protein is most abundant.
  4. Describe how a MECP2 mutation causes the major phenotype of RTT.


CEU Course Syllabus

  Genetics Background and the MECP2 gene     0.8 Contact Hours 
  Affected Genetic Pathways   0.8 Contact Hours
  Developmental Delay   1.2 Contact Hours  
  Long Tern Surveillance   1.2 Contact Hours

Total = 4 Contact Hours

Instructional level:  Intermediate

Did you know you can now get UNLIMITED Continuing Education Credit Hours for only $95/year?
Click Here to learn more.

Course Date: 2017-10-02

Content License

Our courseware includes the text content found on our websites as well as video, audio, and exam questions that make up our courses. You can link to and access our courseware free of charge for personal use. You may not modify or redistribute our courseware under any circumstances.

Although we allow free access for personal use, you may not use our courseware for any commercial purposes without an agreement in place. This includes (but is not limited to) using our courseware for internal training, redistributing our courseware for sale, and copying all or parts of any of our courseware.

If you're interested in licensing our content for commercial purposes or have any other questions, please contact legal@edcompassedu.com.

Proprietary Interest Policy

We will disclose, in advance, any proprietary interest in any product, instrument, device, service, or material to be discussed during the learning event, as well as the source of any third-party compensation related to the presentation. This policy applies to both our organization and contractors. If such proprietary/financial interests exist, we will publish a disclaimer in marketing or instructional materials for a course.

No conflict of interest or relevant financial relationship was identified for this learning activity for individuals in a position to control content.

System Requirements

In order to view this course, you will need to be able to view a PDF document for the course material. If your device doesn't have the capability to view a PDF, you can click here to download Adobe Acrobat for free.

Special Needs

If you require ADA or other special needs accommodations, please contact us by email: support@flextherapistceus.com or by phone 1-800-413-9636, so arrangements can be made.

Board Approval Status

I am a:

Practicing in:

The board approval status information is provided based on our current understanding of the licensing agencies. Please note that it is the responsibility of each licensee to verify acceptance of our courses with their licensing agency.

‹ Return to Courses